中国胸心血管外科临床杂志

中国胸心血管外科临床杂志

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外科手术与介入封堵治疗小儿动脉导管未闭的对照研究

扶剑 , 潘征夏

重庆医科大学附属儿童医院胸心外科，儿童发育疾病研究教育部重点实验室，儿科学重庆市重点实验室（重庆 400014）

收稿日期: 2018-11-08;  修回日期:2018-12-31; 

基金项目: 国家临床重点专科建设项目（国卫办医函[2013]544号）

通讯作者: 潘征夏, Email: 1126149732@qq.com

Comparative study of surgical and interventional closure for the treatment of patent ductus arteriosus in children

FU Jian , PAN Zhengxia

Department of Cardiac Surgery of Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqiong Key Laboratory of Pediatrics, Chongqing, 400014, P.R.China

Corresponding Author: PAN Zhengxia, Email: 1126149732@qq.com

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目的 比较不同手术方式对小儿动脉导管未闭的治疗效果。 方法 回顾性分析 2016 年 1 月 1 日至 2017 年 12 月 31 日于我院心胸外科行手术治疗的先天性动脉导管未闭患儿 38 例为观察组（动脉导管未闭切断缝合术 12 例，动脉导管未闭结扎术 26 例，男 14 例、女 24 例，年龄 0.08～8.67 岁）。随机抽取同期于心内科行介入封堵术的动脉导管未闭患儿 38 例为对照组（均行介入封堵术，男 17 例、女 21 例，年龄 0.5～5.42 岁）。比较两组患儿临床效果。 结果 观察组手术时间、术后住院时间、输血情况均要多于对照组，差异有统计学意义（P<0.05），而两组患儿术中出血量、术后并发症情况方面差异均无统计学意义（P>0.05）。 结论 单一动脉导管未闭或者管径较小的患儿，行介入封堵术创伤更小、恢复更快，而对于低体重、早产儿、合并有其他心内畸形或导管粗大、合并中-重度肺动脉高压情况的动脉导管未闭的患儿，外科手术更加合适。

Objective To study effect of different surgical treatments for patent ductus arteriosus in children. Method A total of 38 patients with patent ductus arteriosus who underwent surgical treatment of cardiothoracic surgery between January 2016 and December 2017 in our hospital were used as an observation group (12 patients with severing suture, 26 patients with ligation, 14 males and 24 females, aged 0.08–8.67 years). In the same period, 38 patients with patent ductus arteriosus who underwent interventional closure in the Department of Cardiology were as a control group (17 males and 21 females, aged 0.5–5.42 years). The clinical effectiveness of the two groups was compared. Results The operation time, postoperative hospital stay, and blood transfusion rate in the observation group were higher than those in the control group with statistical difference (P<0.05). There was no statistical difference in intraoperative blood loss and complications between the two groups. Conclusions In patients with a single patent ductus arteriosus or a small catheter, interventional closure of the patent ductus arteriosus is less trauma and faster recovery. But in patients with lower weigh, premature, other intracardiac malformations, large catheter, moderate or severe pulmonary hypertension, the surgery is better.

关键词: 动脉导管未闭; 外科手术; 介入封堵术

Key words: Patent ductus arteriosus; surgery; interventional closure

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