中国胸心血管外科临床杂志

中国胸心血管外科临床杂志

药物涂层支架时代--冠状动脉旁路移植材料的变化

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药物涂层支架的临床应用对心外科冠状动脉旁路移植术形成了很大的冲击,甚至有人认为可以替代外科手术治疗。但是从临床实践中逐渐认识到,药物涂层支架并没有达到理想的效果,术后中长期死亡率和心绞痛的复发率与金属裸支架相比并无显著的改善,与外科手术相比也无差异。面对药物涂层支架的挑战,心外科在冠状动脉旁路移植材料的取材领域进行了多方面的实践并取得了进展。现就药物涂层支架临床应用后冠状动脉旁路移植材料的变化进行综述。

Drug-eluting stents have great impact to the coronary artery bypass grafting(CABG) in cardiac surgery. Someone even believes that it could replace the surgery procedure. However, the drug-eluting stents are not so ideally in the clinic practice. There are no significant difference between drug-eluting stents and bare metal stents in the mortality and the angina recurrence in middle-long term follow-up. The same results are in the compare with the CABG. As the challenge of the drug-eluting stents, the cardiac surgery has many aspects practice and progress in the harvest of the bypass graft. In the article, the change of the CABG conduit in the era of drug-eluting stents are reviewed.

关键词: 移植材料; 冠状动脉旁路移植术; 药物涂层支架; 金属裸支架

Key words: Graft; Coronary artery bypass grafting; Drug-eluting stent; Bare metal stent

引用本文: 肖锋,杨阳. 药物涂层支架时代--冠状动脉旁路移植材料的变化. 中国胸心血管外科临床杂志, 2007, 14(6): 452-. doi: 复制

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