中国胸心血管外科临床杂志

中国胸心血管外科临床杂志

新辅助化疗对T1~2N0M0期小细胞肺癌治疗的价值

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小细胞肺癌是肺癌中恶性程度较高的一种病理类型,具有与非小细胞肺癌不同的生物学特点,如生长快、恶性程度高、预后差,且易发生纵隔淋巴结及远处转移。近年来对于小细胞肺癌的治疗一直停滞不前,各种治疗方式效果较差。手术的主要适用于 T1~2N0M0 小细胞肺癌的患者,小细胞肺癌对化疗有较强的敏感性,但新辅助化疗在 T1~2N0M0 小细胞肺癌的临床应用尚存争议。本文就新辅助化疗在 T1~2N0M0 小细胞肺癌治疗的价值中做一综述。

Small cell lung cancer is a pathological type with higher malignancy in lung cancer, and has biological characteristics different from non-small cell lung cancer, such as rapid growth, high malignancy and poor prognosis. Mediastinal lymph node and distant metastasis happened frequently. In recent years, the treatment of limited stage small cell lung cancer has been stagnant, various treatments are poor. The operation is mainly suitable for patients with small cell lung cancer (T1-2N0M0). Small cell lung cancer has strong sensitivity to chemotherapy, but the clinical application of neoadjuvant chemotherapy in (T1-2N0M0) small cell lung cancer remains controversial. This article reviews the value of neoadjuvant chemotherapy in the treatment of limited stage small cell lung cancer.

关键词: 小细胞肺癌; 新辅助化疗

Key words: Small cell lung cancer; neoadjuvant chemotherapy

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